Please consider my analysis of the classic observations of multiple sclerosis at www.multiple-sclerosis-abc.org. It reveals specific cerebral and spinal lesion formations, the peculiar features of which are only to be explained by venous back-jets. And these back-jets can be interrupted by surgical interventions. The distinctive traits of the Dawson-fingers, specific cerebral lesion formations, are now to be reliably identified also in vivo owing to advances in serial MR imaging (www.med.harvard.edu/AANLIB/cases/case5/mr2/020.html), 3D lesion-modeling, and MR venography. With this progress there has opened up an opportunity for vascular surgery to cure hopeless cases of MS. Can you be of help? Ramon