Clinical Overview
A blister is a skin irritation caused by pressure from friction when the skin rubs against another surface. A blister occurs when friction causes a small tear in the epidermis, the outermost layer of skin. A space forms between the epidermis and the underlying layers, leaving the skin intact. Fluid seeps into the space, and the blister forms a bubble like appearance. Common areas for blister formation are the hands and feet. Feet often form blisters due to poorly fitting shoes, whereas hands are more likely to form blisters from gripping something, like a tennis racket. Moist skin is more susceptible to blistering than dry skin, and warm conditions also aid blister formation.

Last updated: Jan-01-00