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January 07, 2009  
EDUCATION CENTER: Wound Procedures
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  • Temporary Skin Substitute

    Overview
    Human-derived temporary skin substitute is a temporary covering for damaged epidermal tissue that researchers developed using tissue engineering technology. Doctors use temporary skin substitute on third-degree burns and second-degree burns. Also, doctors use temporary skin substitute to treat skin graft donor sites.

    Detailed Description
    Human-derived temporary skin substitute comprises a polymer membrane and skin cells called fibroblasts. These cells are derived from neonatal human fibroblasts. In a laboratory, tissue engineers culture these cells onto a nylon mesh. The nylon mesh is coated with collagen derived from pig skin, and bonded to the polymer membrane. The membrane is transparent and allows doctors to visually monitor the wound bed. It also serves to help protect the wound from contamination and disturbance.

    Last updated: 19-May-04

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